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3, so it had been unlikely that there was multicollinearity from the multiple linear regression versions. Also, we executed sensitivity analyses by using urinary creatinine concentration (log-remodeled) being a covariate in lieu of creatinine-modified urinary major metal concentrations and together with interaction conditions amongst both toxic major metals (As, Cd, and Pb) or Se; none of the urinary creatinine concentration and also the conversation conditions was statistically substantial, and Over-all associations between urinary significant metals and blood pressure did not adjust (Tables S1 and S2).

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一般社団法人 日本プライマリ・ケア連合学会 予防医療・健康増進委員会 予防医療チーム

The key strength of this examine was that the urine samples were gathered in 17 communities with numerous traits throughout four Asian international locations; this enabled an impartial investigation of associations in between urinary heavy metallic concentrations and blood pressure level in the local stage. Examine limitations involved measuring the whole As concentrations of the urine samples devoid more info of speciation Evaluation to differentiate among publicity to toxic inorganic As and non-poisonous natural and organic As compounds. Moreover, we assessed heavy steel publicity ranges working with single place urine samples. To evaluate the systemic body burdens of Pb and Se, it might are actually helpful to look at their concentrations in whole blood, erythrocytes, or serum/plasma samples [71, 72].

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現在日本で広く行われている健康診査、検診がこの二次予防に当たります。そして、症状が発生した後、病気の

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